Form 8.3 - SHIRE PLC

LONDON--()--

FORM 8.3

PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY

A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE

Rule 8.3 of the Takeover Code (the “Code”)

1. KEY INFORMATION

(a)   Identity of the person whose positions/dealings   Barclays PLC.
  are being disclosed:  
(b) Owner or controller of interest and short
  positions disclosed, if different from 1(a):  
(c) Name of offeror/offeree in relation to whose SHIRE PLC
  relevant securities this form relates:  
(d) If an exempt fund manager connected with an
offeror/offeree, state this and specify identity of
  offeror/offeree:  
(e) Date position held/dealing undertaken: 10 July 2014
(f) Has the discloser previously disclosed, or are YES:
they today disclosing, under the Code in respect ABBVIE INC
  of any other party to this offer?  

2. POSITIONS OF THE PERSON MAKING THE DISCLOSURE

(a) Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates following the dealing (if any)

Class of relevant security:       ORD
Interests   Short Positions
    Number   (%) Number   (%)
(1) Relevant securities owned
and/or controlled: 7,486,060 1.27% 2,723,395 0.46%
           
(2) Derivatives (other than
options): 629,320 0.11% 2,464,094 0.42%
           
(3) Options and agreements to
purchase/sell: 853,400 0.14% 1,763,238 0.30%
           
TOTAL:
8,968,780 1.52% 6,950,727 1.18%

All interests and all short positions should be disclosed.

Details of any open derivative or option positions, or agreements to purchase or sell relevant securities, should be given on a Supplemental Form 8 (Open Positions).

(b) Rights to subscribe for new securities (including directors’ and other executive options)

Class of relevant security in relation to which subscription right exists:  
Details, including nature of the rights concerned and relevant percentages:  

If there are positions or rights to subscribe to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2(a) or (b) (as appropriate) for each additional class of relevant security.

3. DEALINGS (IF ANY) BY THE PERSON MAKING THE DISCLOSURE

(a) Purchases and sales

Class of relevant   Purchase/sale   Number of   Price per unit
security   securities  
ORD Purchase 16 45.2850 GBP
ORD Purchase 25 45.2210 GBP
ORD Purchase 27 45.0810 GBP
ORD Purchase 27 45.3810 GBP
ORD Purchase 43 45.1250 GBP
ORD Purchase 43 45.2460 GBP
ORD Purchase 45 45.8300 GBP
ORD Purchase 52 45.3110 GBP
ORD Purchase 52 45.3390 GBP
ORD Purchase 54 45.7700 GBP
ORD Purchase 62 46.2950 GBP
ORD Purchase 66 44.9450 GBP
ORD Purchase 66 44.9900 GBP
ORD Purchase 66 45.0820 GBP
ORD Purchase 66 45.2900 GBP
ORD Purchase 66 45.3750 GBP
ORD Purchase 66 45.4700 GBP
ORD Purchase 66 45.5300 GBP
ORD Purchase 66 45.5400 GBP
ORD Purchase 66 45.5900 GBP
ORD Purchase 66 45.7050 GBP
ORD Purchase 66 45.7200 GBP
ORD Purchase 66 45.7300 GBP
ORD Purchase 66 45.7400 GBP
ORD Purchase 66 46.1750 GBP
ORD Purchase 66 46.1800 GBP
ORD Purchase 66 46.2350 GBP
ORD Purchase 66 46.3250 GBP
ORD Purchase 66 46.4700 GBP
ORD Purchase 66 46.5150 GBP
ORD Purchase 71 45.0420 GBP
ORD Purchase 71 46.1000 GBP
ORD Purchase 71 46.3200 GBP
ORD Purchase 73 45.4550 GBP
ORD Purchase 73 45.5550 GBP
ORD Purchase 73 46.3300 GBP
ORD Purchase 74 46.1600 GBP
ORD Purchase 75 45.1010 GBP
ORD Purchase 75 45.5492 GBP
ORD Purchase 76 46.3100 GBP
ORD Purchase 77 45.5850 GBP
ORD Purchase 78 45.3050 GBP
ORD Purchase 81 45.0900 GBP
ORD Purchase 82 45.1850 GBP
ORD Purchase 84 46.4350 GBP
ORD Purchase 85 45.7500 GBP
ORD Purchase 87 45.0540 GBP
ORD Purchase 87 45.2650 GBP
ORD Purchase 87 45.6600 GBP
ORD Purchase 89 45.5950 GBP
ORD Purchase 91 45.0100 GBP
ORD Purchase 91 45.0250 GBP
ORD Purchase 94 45.9200 GBP
ORD Purchase 96 45.1550 GBP
ORD Purchase 97 45.2110 GBP
ORD Purchase 97 45.6150 GBP
ORD Purchase 98 45.2950 GBP
ORD Purchase 98 45.4050 GBP
ORD Purchase 99 46.2400 GBP
ORD Purchase 100 45.4200 GBP
ORD Purchase 100 45.7100 GBP
ORD Purchase 105 45.3010 GBP
ORD Purchase 106 45.6100 GBP
ORD Purchase 113 45.1400 GBP
ORD Purchase 113 46.1900 GBP
ORD Purchase 113 46.3450 GBP
ORD Purchase 114 46.3550 GBP
ORD Purchase 114 46.5450 GBP
ORD Purchase 118 45.3600 GBP
ORD Purchase 118 46.3500 GBP
ORD Purchase 120 46.5010 GBP
ORD Purchase 123 45.1540 GBP
ORD Purchase 125 45.0850 GBP
ORD Purchase 132 45.6850 GBP
ORD Purchase 132 45.7250 GBP
ORD Purchase 132 46.3900 GBP
ORD Purchase 134 45.4950 GBP
ORD Purchase 135 45.4850 GBP
ORD Purchase 139 45.1600 GBP
ORD Purchase 139 45.1650 GBP
ORD Purchase 139 45.6950 GBP
ORD Purchase 139 45.8750 GBP
ORD Purchase 140 45.8700 GBP
ORD Purchase 145 45.8400 GBP
ORD Purchase 146 45.0150 GBP
ORD Purchase 148 46.2100 GBP
ORD Purchase 149 45.4210 GBP
ORD Purchase 156 45.5500 GBP
ORD Purchase 158 45.7690 GBP
ORD Purchase 159 44.9600 GBP
ORD Purchase 160 46.3220 GBP
ORD Purchase 162 45.9250 GBP
ORD Purchase 163 45.0200 GBP
ORD Purchase 163 45.6250 GBP
ORD Purchase 168 45.0700 GBP
ORD Purchase 168 45.4150 GBP
ORD Purchase 173 45.5710 GBP
ORD Purchase 177 45.3800 GBP
ORD Purchase 177 45.7000 GBP
ORD Purchase 186 46.2250 GBP
ORD Purchase 187 45.3100 GBP
ORD Purchase 187 45.9300 GBP
ORD Purchase 193 45.1750 GBP
ORD Purchase 194 45.0450 GBP
ORD Purchase 195 45.6900 GBP
ORD Purchase 196 44.9400 GBP
ORD Purchase 196 45.2050 GBP
ORD Purchase 200 45.1800 GBP
ORD Purchase 203 45.2520 GBP
ORD Purchase 204 45.6700 GBP
ORD Purchase 207 45.3500 GBP
ORD Purchase 212 45.6200 GBP
ORD Purchase 213 45.5000 GBP
ORD Purchase 216 45.2720 GBP
ORD Purchase 220 45.1050 GBP
ORD Purchase 222 46.2600 GBP
ORD Purchase 227 46.3000 GBP
ORD Purchase 243 45.2550 GBP
ORD Purchase 244 45.3200 GBP
ORD Purchase 248 45.4734 GBP
ORD Purchase 250 45.4300 GBP
ORD Purchase 253 45.3900 GBP
ORD Purchase 257 45.2800 GBP
ORD Purchase 266 45.0000 GBP
ORD Purchase 270 45.4000 GBP
ORD Purchase 271 45.4400 GBP
ORD Purchase 277 45.9550 GBP
ORD Purchase 281 44.9500 GBP
ORD Purchase 283 46.2200 GBP
ORD Purchase 287 45.2150 GBP
ORD Purchase 294 45.2750 GBP
ORD (traded as ADR) Purchase 300 238.1500 USD
ORD (traded as ADR) Purchase 300 238.6200 USD
ORD Purchase 312 44.9100 GBP
ORD Purchase 314 46.2700 GBP
ORD Purchase 323 45.1950 GBP
ORD Purchase 327 45.4010 GBP
ORD Purchase 335 45.5600 GBP
ORD Purchase 340 45.5636 GBP
ORD Purchase 341 46.3600 GBP
ORD Purchase 345 45.2100 GBP
ORD Purchase 350 45.9000 GBP
ORD Purchase 356 45.3344 GBP
ORD Purchase 369 45.0400 GBP
ORD Purchase 374 45.7900 GBP
ORD Purchase 377 45.2200 GBP
ORD Purchase 378 45.1300 GBP
ORD Purchase 383 45.5800 GBP
ORD Purchase 400 45.1200 GBP
ORD Purchase 413 45.1500 GBP
ORD Purchase 424 45.2010 GBP
ORD Purchase 477 45.6800 GBP
ORD Purchase 495 45.2189 GBP
ORD Purchase 528 45.1700 GBP
ORD Purchase 556 45.3000 GBP
ORD Purchase 570 46.2900 GBP
ORD (traded as ADR) Purchase 600 237.3150 USD
ORD (traded as ADR) Purchase 600 237.9250 USD
ORD (traded as ADR) Purchase 600 238.0325 USD
ORD (traded as ADR) Purchase 600 238.5600 USD
ORD (traded as ADR) Purchase 600 238.6150 USD
ORD Purchase 622 45.2400 GBP
ORD Purchase 636 45.9503 GBP
ORD Purchase 636 45.9600 GBP
ORD Purchase 639 45.9100 GBP
ORD Purchase 650 46.1700 GBP
ORD Purchase 653 45.0500 GBP
ORD Purchase 727 45.2700 GBP
ORD Purchase 764 45.6000 GBP
ORD (traded as ADR) Purchase 780 238.4576 USD
ORD Purchase 805 45.6079 GBP
ORD Purchase 855 45.5753 GBP
ORD Purchase 858 45.0800 GBP
ORD (traded as ADR) Purchase 900 237.7700 USD
ORD (traded as ADR) Purchase 900 238.3533 USD
ORD Purchase 901 45.1900 GBP
ORD Purchase 951 45.2300 GBP
ORD (traded as ADR) Purchase 1,023 238.3016 USD
ORD Purchase 1,027 45.3648 GBP
ORD Purchase 1,078 45.2000 GBP
ORD Purchase 1,092 45.1000 GBP
ORD (traded as ADR) Purchase 1,200 238.0300 USD
ORD (traded as ADR) Purchase 1,200 238.2199 USD
ORD Purchase 1,220 45.2600 GBP
ORD (traded as ADR) Purchase 1,329 238.2555 USD
ORD (traded as ADR) Purchase 1,479 236.9413 USD
ORD (traded as ADR) Purchase 1,500 235.8840 USD
ORD Purchase 1,600 45.3139 GBP
ORD (traded as ADR) Purchase 1,650 236.5345 USD
ORD Purchase 1,906 45.1100 GBP
ORD (traded as ADR) Purchase 1,950 233.6288 USD
ORD (traded as ADR) Purchase 2,100 236.9754 USD
ORD Purchase 2,132 45.0600 GBP
ORD Purchase 2,214 45.3381 GBP
ORD Purchase 2,437 45.4807 GBP
ORD (traded as ADR) Purchase 3,000 236.3600 USD
ORD Purchase 3,038 45.2500 GBP
ORD (traded as ADR) Purchase 3,060 236.9741 USD
ORD Purchase 3,222 45.3073 GBP
ORD Purchase 3,364 46.0031 GBP
ORD (traded as ADR) Purchase 4,374 237.2755 USD
ORD (traded as ADR) Purchase 4,800 236.5258 USD
ORD Purchase 4,990 45.8995 GBP
ORD Purchase 5,115 46.0000 GBP
ORD (traded as ADR) Purchase 5,400 234.6600 USD
ORD (traded as ADR) Purchase 5,403 238.3756 USD
ORD Purchase 5,510 45.3400 GBP
ORD Purchase 5,580 45.6605 GBP
ORD (traded as ADR) Purchase 6,000 237.8995 USD
ORD (traded as ADR) Purchase 6,150 236.7561 USD
ORD (traded as ADR) Purchase 6,300 233.5819 USD
ORD (traded as ADR) Purchase 6,300 236.3619 USD
ORD Purchase 6,431 45.6041 GBP
ORD (traded as ADR) Purchase 6,915 232.3240 USD
ORD Purchase 6,997 45.3784 GBP
ORD Purchase 7,238 45.4500 GBP
ORD (traded as ADR) Purchase 8,700 235.8660 USD
ORD Purchase 8,897 45.4314 GBP
ORD (traded as ADR) Purchase 9,171 236.5070 USD
ORD (traded as ADR) Purchase 9,300 236.3612 USD
ORD Purchase 9,414 45.3469 GBP
ORD Purchase 12,472 45.3678 GBP
ORD (traded as ADR) Purchase 12,900 238.3728 USD
ORD Purchase 14,035 45.8596 GBP
ORD (traded as ADR) Purchase 15,372 237.4025 USD
ORD (traded as ADR) Purchase 15,426 235.7459 USD
ORD Purchase 15,684 45.7704 GBP
ORD Purchase 17,245 45.2887 GBP
ORD (traded as ADR) Purchase 17,400 237.6328 USD
ORD (traded as ADR) Purchase 21,624 238.3699 USD
ORD Purchase 23,700 45.0434 GBP
ORD (traded as ADR) Purchase 30,906 235.4589 USD
ORD Purchase 31,783 45.4395 GBP
ORD Purchase 31,972 45.6184 GBP
ORD Purchase 34,359 45.4333 GBP
ORD (traded as ADR) Purchase 35,400 236.7607 USD
ORD Purchase 38,617 45.5547 GBP
ORD Purchase 50,000 44.8576 GBP
ORD Purchase 64,000 45.4253 GBP
ORD Purchase 127,889 45.7088 GBP
ORD Purchase 130,775 45.5535 GBP
ORD Sale 16 45.2850 GBP
ORD (traded as ADR) Sale 24 237.8200 USD
ORD Sale 25 45.2210 GBP
ORD Sale 27 45.0810 GBP
ORD Sale 27 45.3810 GBP
ORD Sale 43 45.1250 GBP
ORD Sale 43 45.2460 GBP
ORD Sale 45 45.8300 GBP
ORD Sale 52 45.3110 GBP
ORD Sale 52 45.3390 GBP
ORD Sale 54 45.7700 GBP
ORD Sale 62 46.2950 GBP
ORD Sale 66 44.9450 GBP
ORD Sale 66 44.9900 GBP
ORD Sale 66 45.0820 GBP
ORD Sale 66 45.2900 GBP
ORD Sale 66 45.3750 GBP
ORD Sale 66 45.4700 GBP
ORD Sale 66 45.5300 GBP
ORD Sale 66 45.5400 GBP
ORD Sale 66 45.5900 GBP
ORD Sale 66 45.7050 GBP
ORD Sale 66 45.7200 GBP
ORD Sale 66 45.7300 GBP
ORD Sale 66 45.7400 GBP
ORD Sale 66 46.1750 GBP
ORD Sale 66 46.1800 GBP
ORD Sale 66 46.2350 GBP
ORD Sale 66 46.3250 GBP
ORD Sale 66 46.4700 GBP
ORD Sale 66 46.5150 GBP
ORD Sale 67 45.3350 GBP
ORD Sale 71 45.0420 GBP
ORD Sale 71 46.1000 GBP
ORD Sale 71 46.3200 GBP
ORD (traded as ADR) Sale 72 231.7400 USD
ORD Sale 73 45.4550 GBP
ORD Sale 73 45.5550 GBP
ORD Sale 73 46.3300 GBP
ORD Sale 74 46.1600 GBP
ORD Sale 75 45.1010 GBP
ORD Sale 76 46.3100 GBP
ORD Sale 77 45.5850 GBP
ORD Sale 78 45.3050 GBP
ORD Sale 82 45.1850 GBP
ORD Sale 84 46.4350 GBP
ORD Sale 85 45.7500 GBP
ORD Sale 87 45.0540 GBP
ORD Sale 87 45.2650 GBP
ORD Sale 87 45.6600 GBP
ORD Sale 89 45.5950 GBP
ORD Sale 91 45.0100 GBP
ORD Sale 91 45.0250 GBP
ORD Sale 94 45.9200 GBP
ORD Sale 96 45.1550 GBP
ORD Sale 97 45.2110 GBP
ORD Sale 97 45.6150 GBP
ORD Sale 98 45.2950 GBP
ORD Sale 98 45.4050 GBP
ORD Sale 99 46.2400 GBP
ORD Sale 100 45.4200 GBP
ORD Sale 100 45.7100 GBP
ORD Sale 105 45.3010 GBP
ORD Sale 106 45.6100 GBP
ORD Sale 113 45.1400 GBP
ORD Sale 113 46.1900 GBP
ORD Sale 113 46.3450 GBP
ORD Sale 114 46.3550 GBP
ORD Sale 114 46.5450 GBP
ORD Sale 116 45.3400 GBP
ORD Sale 118 45.3600 GBP
ORD Sale 118 46.3500 GBP
ORD Sale 120 46.5010 GBP
ORD Sale 123 45.1540 GBP
ORD Sale 125 45.0850 GBP
ORD Sale 132 45.6850 GBP
ORD Sale 132 45.7250 GBP
ORD Sale 132 46.3900 GBP
ORD Sale 134 45.4950 GBP
ORD Sale 135 45.4850 GBP
ORD Sale 139 45.1600 GBP
ORD Sale 139 45.1650 GBP
ORD Sale 139 45.6950 GBP
ORD Sale 139 45.8750 GBP
ORD Sale 140 45.8700 GBP
ORD Sale 145 45.8400 GBP
ORD Sale 146 45.0150 GBP
ORD Sale 148 46.2100 GBP
ORD Sale 149 45.4210 GBP
ORD Sale 156 45.0900 GBP
ORD Sale 156 45.5500 GBP
ORD Sale 158 45.7690 GBP
ORD Sale 159 44.9600 GBP
ORD Sale 160 46.3220 GBP
ORD Sale 162 45.9250 GBP
ORD Sale 163 45.0200 GBP
ORD Sale 163 45.6250 GBP
ORD Sale 168 45.0700 GBP
ORD Sale 168 45.4150 GBP
ORD (traded as ADR) Sale 168 233.6200 USD
ORD Sale 173 45.5710 GBP
ORD Sale 177 45.3800 GBP
ORD Sale 177 45.7000 GBP
ORD Sale 186 46.2250 GBP
ORD Sale 187 45.3100 GBP
ORD Sale 187 45.9300 GBP
ORD Sale 193 45.1750 GBP
ORD Sale 194 45.0450 GBP
ORD Sale 195 45.6900 GBP
ORD Sale 196 44.9400 GBP
ORD Sale 196 45.2050 GBP
ORD Sale 200 45.1800 GBP
ORD Sale 203 45.2520 GBP
ORD Sale 204 45.6700 GBP
ORD Sale 207 45.3500 GBP
ORD Sale 212 45.6200 GBP
ORD Sale 213 45.5000 GBP
ORD Sale 216 45.2720 GBP
ORD Sale 220 45.1050 GBP
ORD Sale 222 46.2600 GBP
ORD Sale 227 46.3000 GBP
ORD Sale 242 45.4300 GBP
ORD Sale 243 45.2550 GBP
ORD Sale 244 45.3200 GBP
ORD Sale 253 45.3900 GBP
ORD Sale 257 45.2800 GBP
ORD Sale 266 45.0000 GBP
ORD Sale 270 45.4000 GBP
ORD Sale 271 45.4400 GBP
ORD Sale 277 45.9550 GBP
ORD Sale 281 44.9500 GBP
ORD Sale 283 46.2200 GBP
ORD Sale 287 45.2150 GBP
ORD Sale 294 45.2750 GBP
ORD (traded as ADR) Sale 300 230.8000 USD
ORD (traded as ADR) Sale 300 230.9300 USD
ORD (traded as ADR) Sale 300 231.9400 USD
ORD (traded as ADR) Sale 300 233.4800 USD
ORD (traded as ADR) Sale 300 236.8100 USD
ORD (traded as ADR) Sale 300 238.0150 USD
ORD Sale 312 44.9100 GBP
ORD Sale 314 46.2700 GBP
ORD Sale 323 45.1950 GBP
ORD Sale 327 45.4010 GBP
ORD Sale 335 45.5600 GBP
ORD Sale 341 46.3600 GBP
ORD Sale 345 45.2100 GBP
ORD Sale 350 45.9000 GBP
ORD Sale 357 46.2645 GBP
ORD Sale 369 45.0400 GBP
ORD Sale 374 45.7900 GBP
ORD Sale 377 45.2200 GBP
ORD Sale 378 45.1300 GBP
ORD Sale 383 45.5800 GBP
ORD Sale 400 45.1200 GBP
ORD Sale 413 45.1500 GBP
ORD Sale 424 45.2010 GBP
ORD Sale 456 45.6500 GBP
ORD Sale 477 45.6800 GBP
ORD Sale 528 45.1700 GBP
ORD Sale 556 45.3000 GBP
ORD Sale 570 46.2900 GBP
ORD (traded as ADR) Sale 600 236.8320 USD
ORD (traded as ADR) Sale 600 238.0325 USD
ORD Sale 609 45.5893 GBP
ORD Sale 622 45.2400 GBP
ORD (traded as ADR) Sale 636 233.7396 USD
ORD Sale 639 45.9100 GBP
ORD Sale 645 45.2434 GBP
ORD Sale 651 46.1700 GBP
ORD Sale 653 45.0500 GBP
ORD Sale 727 45.2700 GBP
ORD Sale 753 46.0803 GBP
ORD Sale 764 45.6000 GBP
ORD (traded as ADR) Sale 846 233.6001 USD
ORD Sale 858 45.0800 GBP
ORD (traded as ADR) Sale 900 236.8000 USD
ORD (traded as ADR) Sale 900 236.9300 USD
ORD (traded as ADR) Sale 900 238.0000 USD
ORD (traded as ADR) Sale 900 238.0166 USD
ORD (traded as ADR) Sale 900 238.5860 USD
ORD Sale 901 45.1900 GBP
ORD Sale 951 45.2300 GBP
ORD Sale 1,078 45.2000 GBP
ORD Sale 1,092 45.1000 GBP
ORD (traded as ADR) Sale 1,200 238.0300 USD
ORD (traded as ADR) Sale 1,200 238.4400 USD
ORD Sale 1,220 45.2600 GBP
ORD Sale 1,616 45.1487 GBP
ORD (traded as ADR) Sale 1,800 236.8266 USD
ORD Sale 1,906 45.1100 GBP
ORD (traded as ADR) Sale 2,100 238.0217 USD
ORD Sale 2,132 45.0600 GBP
ORD (traded as ADR) Sale 2,700 235.0700 USD
ORD (traded as ADR) Sale 3,000 234.0260 USD
ORD (traded as ADR) Sale 3,000 236.7560 USD
ORD Sale 3,038 45.2500 GBP
ORD (traded as ADR) Sale 3,900 236.7346 USD
ORD (traded as ADR) Sale 5,700 234.5668 USD
ORD (traded as ADR) Sale 5,700 236.1622 USD
ORD Sale 6,015 45.2713 GBP
ORD Sale 6,180 46.0000 GBP
ORD (traded as ADR) Sale 6,300 236.7214 USD
ORD Sale 7,325 45.1403 GBP
ORD (traded as ADR) Sale 7,500 237.1237 USD
ORD (traded as ADR) Sale 7,500 237.9000 USD
ORD Sale 8,058 45.2015 GBP
ORD Sale 8,998 45.5273 GBP
ORD Sale 9,132 45.3913 GBP
ORD Sale 9,336 45.5716 GBP
ORD Sale 10,859 45.3466 GBP
ORD Sale 10,860 45.3730 GBP
ORD (traded as ADR) Sale 11,100 236.2244 USD
ORD (traded as ADR) Sale 12,000 238.3568 USD
ORD Sale 13,844 45.8004 GBP
ORD Sale 14,609 45.3346 GBP
ORD Sale 15,835 45.4174 GBP
ORD (traded as ADR) Sale 17,700 236.7607 USD
ORD (traded as ADR) Sale 18,600 236.3612 USD
ORD (traded as ADR) Sale 19,425 234.8452 USD
ORD (traded as ADR) Sale 27,900 236.5337 USD
ORD Sale 29,411 45.6282 GBP
ORD Sale 29,447 45.3975 GBP
ORD (traded as ADR) Sale 31,356 235.1968 USD
ORD Sale 32,069 45.4855 GBP
ORD Sale 32,148 45.3676 GBP
ORD Sale 32,353 45.5892 GBP
ORD Sale 50,000 45.5114 GBP
ORD Sale 77,991 45.4490 GBP
ORD Sale 101,502 45.7197 GBP
ORD Sale 106,755 45.3837 GBP

(b) Derivatives transactions (other than options)

Class of   Product   Nature of dealing   Number of   Price per
relevant description reference unit
security     securities  
ORD SWAP Long 196 45.6381 GBP
ORD SWAP Long 248 46.0396 GBP
ORD SWAP Long 361 45.2799 GBP
ORD SWAP Long 500 46.0000 GBP
ORD SWAP Long 641 46.0043 GBP
ORD CFD Long 645 45.2434 GBP
ORD CFD Long 2,500 46.3472 GBP
ORD CFD Long 1,616 45.1487 GBP
ORD SWAP Long 6,002 45.2847 GBP
ORD CFD Long 11,001 45.3161 GBP
ORD CFD Long 18,872 45.3732 GBP
ORD SWAP Short 15 46.3913 GBP
ORD SWAP Short 195 45.3617 GBP
ORD SWAP Short 500 46.0000 GBP
ORD CFD Short 636 45.9502 GBP
ORD CFD Short 636 45.9656 GBP
ORD SWAP Short 1,178 45.2100 GBP
ORD CFD Short 3,222 45.3073 GBP
ORD SWAP Short 3,349 46.0013 GBP
ORD CFD Short 5,788 45.2801 GBP
ORD SWAP Short 6,339 45.3391 GBP
ORD CFD Short 6,960 45.3843 GBP
ORD CFD Short 8,400 46.0041 GBP
ORD CFD Short 4,990 45.8995 GBP
ORD CFD Short 8,192 45.8780 GBP
ORD SWAP Short 64,000 45.4253 GBP

(c) Options transactions in respect of existing securities

(i) Writing, selling, purchasing or varying

Class   Product   Writing,   Number   Exercise   Type   Expiry   Option
of description purchasing, of price date money
relevant selling, securities per unit paid/
security varying etc to which received
option per unit
      relates        
ADR Call Options Purchasing 5,100 255 USD American 19 Jul 2014 4.5576 USD
ADR Call Options Selling 200 200 USD American 18 Oct 2014 40.7500 USD
ADR Call Options Selling 5,100 235 USD American 19 Jul 2014 13.3076 USD
ADR Call Options Selling 15,000 240 USD American 19 Jul 2014 9.5386 USD
ADR Call Options Selling 100 240 USD American 18 Oct 2014 18.9000 USD
ADR Call Options Selling 5,000 245 USD American 19 Jul 2014 8.0000 USD
ADR Put Options Selling 15,000 230 USD American 19 Jul 2014 7.5363 USD

(ii) Exercising

Class of relevant security   Product description

e.g. call option

  Number of securities   Exercise price per unit

(d) Other dealings (including subscribing for new securities)

Class of relevant security   Nature of dealing

e.g. subscription, conversion

  Details   Price per unit (if applicable)

The currency of all prices and other monetary amounts should be stated.

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

4. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the person making the disclosure and any party to the offer or any person acting in concert with a party to the offer:

If there are no such agreements, arrangements or understandings, state “none”

NONE

(b) Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between the person making the disclosure and any other person relating to:

(i) the voting rights of any relevant securities under any option; or

(ii) the voting rights or future acquisition or disposal of any relevant securities to which any derivative is referenced:

If there are no such agreements, arrangements or understandings, state “none”

NONE

(c) Attachments

Is a Supplemental Form 8 (Open Positions) attached?   YES
Date of disclosure: 11 Jul 2014
Contact name: Rajesh Muthanna
Telephone number: 020 3555 4634

Public disclosures under Rule 8 of the Code must be made to a Regulatory Information Service and must also be emailed to the Takeover Panel at monitoring@disclosure.org.uk. The Panel’s Market Surveillance Unit is available for consultation in relation to the Code’s dealing disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel’s website at www.thetakeoverpanel.org.uk.

143221.01

SUPPLEMENTAL FORM 8 (OPEN POSITIONS)

DETAILS OF OPEN OPTION AND DERIVATIVE POSITIONS, AGREEMENTS TO PURCHASE OR SELL ETC.

Note 5(i) on Rule 8 of the Takeover Code (the “Code”)

1. KEY INFORMATION

Identity of the person whose positions/dealings   Barclays PLC.
are being disclosed:  
Name of offeror/offeree in relation to whose SHIRE PLC
relevant securities this from relates:  

2. OPTIONS AND DERIVATIVES

Class   Product   Writing,   Number   Exercise   Type   Expiry
of description purchasing, of price date
relevant selling, securities per unit
security varying etc to which
option
      relates      
ORD Call Options Purchased 2,000 3700.0000 GBP European 18 Jul 2014
ADR Put Options Purchased -300 160.0000 American 18 Oct 2014
ADR Put Options Purchased -2,800 160.0000 American 17 Jan 2015
ADR Put Options Purchased -600 185.0000 American 17 Jan 2015
ADR Put Options Purchased -200 190.0000 American 18 Oct 2014
ADR Put Options Purchased -900 195.0000 American 19 Jul 2014
ADR Put Options Purchased -1,100 205.0000 American 19 Jul 2014
ADR Put Options Purchased -300 210.0000 American 19 Jul 2014
ADR Put Options Purchased -100 215.0000 American 16 Aug 2014
ADR Put Options Purchased -473 220.0000 American 18 Jul 2014
ADR Put Options Purchased -1,400 220.0000 American 19 Jul 2014
ADR Put Options Purchased -100 220.0000 American 16 Aug 2014
ADR Put Options Purchased -500 230.0000 American 18 Oct 2014
ADR Put Options Purchased -1,000 260.0000 American 18 Oct 2014
ADR Put Options Written 400 110.0000 American 19 Jul 2014
ADR Put Options Written 500 130.0000 American 19 Jul 2014
ADR Put Options Written 400 140.0000 American 19 Jul 2014
ADR Put Options Written 300 145.0000 American 18 Oct 2014
ADR Put Options Written 100 150.0000 American 19 Jul 2014
ADR Put Options Written 300 150.0000 American 18 Oct 2014
ADR Put Options Written 1,300 165.0000 American 19 Jul 2014
ADR Put Options Written 600 165.0000 American 18 Oct 2014
ADR Put Options Written 300 170.0000 American 19 Jul 2014
ADR Put Options Written 500 170.0000 American 18 Oct 2014
ADR Put Options Written 6,700 175.0000 American 19 Jul 2014
ADR Put Options Written 300 180.0000 American 18 Oct 2014
ADR Put Options Written 200 185.0000 American 19 Jul 2014
ADR Put Options Written 700 195.0000 American 18 Oct 2014
ADR Put Options Written 2,200 200.0000 American 19 Jul 2014
ADR Put Options Written 100 200.0000 American 16 Aug 2014
ADR Put Options Written 200 200.0000 American 18 Oct 2014
ADR Put Options Written 300 205.0000 American 18 Oct 2014
ADR Put Options Written 100 210.0000 American 16 Aug 2014
ADR Put Options Written 1,500 215.0000 American 19 Jul 2014
ADR Put Options Written 100 225.0000 American 16 Aug 2014
ADR Put Options Written 113,000 230.0000 American 19 Jul 2014
ADR Put Options Written 200 230.0000 American 17 Jan 2015
ADR Put Options Written 100 235.0000 American 18 Oct 2014
ADR Put Options Written 1,000 240.0000 American 18 Oct 2014
ADR Put Options Written 300 275.0000 American 18 Oct 2014
ADR Put Options Written 300 280.0000 American 18 Oct 2014
ADR Call Options Purchased 200 130.0000 American 17 Jan 2015
ADR Call Options Purchased 1,800 165.0000 American 18 Oct 2014
ADR Call Options Purchased 1,100 175.0000 American 19 Jul 2014
ADR Call Options Purchased 100 185.0000 American 19 Jul 2014
ADR Call Options Purchased 1,000 195.0000 American 19 Jul 2014
ADR Call Options Purchased 100 240.0000 American 16 Aug 2014
ADR Call Options Purchased 5,900 250.0000 American 19 Jul 2014
ADR Call Options Purchased 134,000 255.0000 American 19 Jul 2014
ADR Call Options Purchased 7,100 260.0000 American 19 Jul 2014
ADR Call Options Purchased 200 270.0000 American 19 Jul 2014
ADR Call Options Purchased 200 280.0000 American 19 Jul 2014
ADR Call Options Purchased 100 280.0000 American 16 Aug 2014
ADR Call Options Written -300 150.0000 American 19 Jul 2014
ADR Call Options Written -1,400 155.0000 American 19 Jul 2014
ADR Call Options Written -1,200 155.0000 American 18 Oct 2014
ADR Call Options Written -2,500 160.0000 American 18 Oct 2014
ADR Call Options Written -200 165.0000 American 19 Jul 2014
ADR Call Options Written -5,200 170.0000 American 19 Jul 2014
ADR Call Options Written -5,800 175.0000 American 18 Oct 2014
ADR Call Options Written -900 180.0000 American 19 Jul 2014
ADR Call Options Written -200 180.0000 American 18 Oct 2014
ADR Call Options Written -100 180.0000 American 17 Jan 2015
ADR Call Options Written -1,600 190.0000 American 19 Jul 2014
ADR Call Options Written -1,100 190.0000 American 18 Oct 2014
ADR Call Options Written -2,300 195.0000 American 18 Oct 2014
ADR Call Options Written -200 200.0000 American 19 Jul 2014
ADR Call Options Written -1,900 200.0000 American 18 Oct 2014
ADR Call Options Written -200 210.0000 American 18 Oct 2014
ADR Call Options Written -473 220.0000 American 18 Jul 2014
ADR Call Options Written -900 220.0000 American 19 Jul 2014
ADR Call Options Written -2,200 220.0000 American 18 Oct 2014
ADR Call Options Written -2,900 230.0000 American 19 Jul 2014
ADR Call Options Written -100 230.0000 American 16 Aug 2014
ADR Call Options Written -1,600 230.0000 American 18 Oct 2014
ADR Call Options Written -500 230.0000 American 17 Jan 2015
ADR Call Options Written -22,600 235.0000 American 19 Jul 2014
ADR Call Options Written -1,000 235.0000 American 18 Oct 2014
ADR Call Options Written -289,600 240.0000 American 19 Jul 2014
ADR Call Options Written -20,000 240.0000 American 16 Aug 2014
ADR Call Options Written -1,200 240.0000 American 18 Oct 2014
ADR Call Options Written -200 240.0000 American 17 Jan 2015
ADR Call Options Written -10,000 245.0000 American 19 Jul 2014
ADR Call Options Written -600 245.0000 American 17 Jan 2015
ADR Call Options Written -176,800 250.0000 American 19 Jul 2014
ADR Call Options Written -18,100 250.0000 American 16 Aug 2014
ADR Call Options Written -100 260.0000 American 16 Aug 2014
ADR Call Options Written -1,000 265.0000 American 17 Jan 2015
ADR Call Options Written -300 270.0000 American 18 Oct 2014
ADR Call Options Written -1,900 270.0000 American 17 Jan 2015
ADR Call Options Written -400 275.0000 American 19 Jul 2014
ADR Call Options Written -300 285.0000 American 19 Jul 2014
ADR Call Options Written -100 320.0000 American 17 Jan 2015

3. AGREEMENTS TO PURCHASE OR SELL ETC.

Full details should be given so that the nature of the interest or position can be fully understood:

It is not necessary to provide details on a Supplemental Form (Open Positions) with regard to contracts for differences (“CFDs”) or spread bets.

The currency of all prices and other monetary amounts should be stated.

The Panel’s Market Surveillance Unit is available for consultation in relation to the Code’s dealing disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel’s website at www.thetakeoverpanel.org.uk.

Short Name: BARCLAYS PLC
Category Code: FEO
Sequence Number: 424270
Time of Receipt (offset from UTC): 20140711T123200+0100

Contacts

BARCLAYS PLC

Contacts

BARCLAYS PLC