DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/8cxv32/il1_signaling) has announced the addition of the "IL-1 Signaling Pathway in Oncology Drug Pipeline Update 2013" report to their offering.
The IL-1 signaling pathway activates the MAPK/JNK signaling modules. The MAPK pathway leads to activation of NFkB complex. As both IL-1 and TNF alpha stimulate the MAPK signaling module and activate NFkB, they are synergistic and complement each other's activity.
There are today 82 companies plus partners developing 76 IL-1 pathway targeting drugs in 285 developmental projects in cancer. In addition, there is 1 suspended drug and the accumulated number of ceased drugs over the last years amount to another 39 drugs. Il-1 Signaling Pathway In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 79 different targets. All included targets have been cross-referenced for the presence of mutations associated with human cancer. To date 75 out of the 78 studied drug targets so far have been recorded with somatic mutations. The software application lets you narrow in on these mutations and links out to the mutational analysis for each of the drug targets for detailed information.
All drugs targets are further categorized on in the software application by 26 classifications of molecular function and with pathway referrals to BioCarta, KEGG, NCI-Nature and NetPath.
Reasons To Buy
- Show investors/board/management that you are right on top of drug development progress in your therapeutic area.
- Find competitors, collaborations partners, M&A candidates etc.
- Jump start competitive drug intelligence operations
- Excellent starting point for world wide benchmarking
- Compare portfolio and therapy focus with your peers
- Speed up pro-active in-/out licensing strategy work
- Fast and easy way of tracking drugs using search engines
For more information visit http://www.researchandmarkets.com/research/8cxv32/il1_signaling
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