PharmaTools Natural Products Multiparameter Libraries
An important new capability in PharmaTools is a new library search capability, that includes a setup to automatically build up libraries, e.g. for natural compounds, have multi-user access to the library (e.g. from various countries), and automatically screen for compounds in the library. The specificity is enhanced by combined searches with positive/negative polarity ESI-measurements, as well as MS and MS/MS data of the same compound. These libraries can be particularly powerful in drug discovery.
PharmaTools Open Access Environment
Bruker Daltonics introduced its Compass(TM) integrated software environment for all of its life-science mass spectrometers one year ago. Compass makes it easy to run different types of Bruker systems in the same laboratory, as they share the same acquisition graphical user interfaces, and use identical processing, analysis and bioinformatics software under the Compass umbrella.
Bruker Daltonics now announces Compass OA, an open access environment for multi-user environments, particularly in large or medium sized pharma or biotech companies. Compass OA allows untrained customers to submit their samples for measurements via a very intuitive simplified acquisition user interface that guides the user step-by-step. Compass OA then also distributes the acquired data and provides powerful visual tools for data interpretation and quick assessment of the results back to the users.
Metabolic Profiler(TM) For Efficacy and Toxicity Studies
The new Metabolic Profiler is a system developed jointly by Bruker Daltonics and Bruker Biospin to study metabolites as surrogate markers for efficacy, or to assess toxicity early on in drug development. Metabolic profiles are compared and differences detected on individual samples or patient cohorts. Samples are analyzed by microTOF(TM) ESI-TOF mass spectrometry and/or one-dimensional flow-NMR, and jointly analyzed in one powerful analysis package.
PharmaTools Validation Products
The PharmaTools suite offers the validation products IQ (installation qualification) and OQ/PV (operational qualification and performance verification). These products increase productivity by ensuring consistent performance of the instruments over time.
For customers in regulated environments, the PharmaTools suite now includes support software for 21 CFR Part 11 compliance, including audit trails, user management, result history, electronic signatures, and data security.
PharmaTools Training, Support and Service Products
Highest quality training, support and service are key to help our pharma customers achieve the utmost in productivity and uptime. We now offer various levels of maintenance service contracts (MSAs), including optional 24/7 coverage, as well as a new preventive maintenance (PM) program, along with the customary per-call service.
In recent years, Bruker Daltonics has considerably expanded its global service and support network in order to provide whatever level of service support is required by global pharma companies, or individual pharma or biotech sites.
Service can now also be provided via remote diagnostics, often accelerating the process of getting customers up and running again. With PharmaTools, our broadened customer training program now includes options for training courses at our applications laboratories, via internet webex sessions, or on-site.
Dr. Michael Schubert, Vice President for R&D at Bruker Daltonics, stated: "The introduction of our PharmaTools suite is a significant step in our development of solutions to meet customer requirements. We are now in an excellent position to expand the use of our high-information content tools within drug discovery. Moreover, we now offer a broad range of tools also for drug development, and even pharma QA/QC, where reliability, validation, service support and creative functional solutions for specific requirements are particularly important. Our easy-to-use, integrated Compass software environment further enhances the productivity for many PharmaTools applications."
ABOUT BRUKER BIOSCIENCES
Bruker BioSciences Corporation, headquartered in Billerica, Massachusetts, is the publicly traded parent company of Bruker AXS Inc. and Bruker Daltonics Inc. Bruker AXS is a leading developer and provider of life science and advanced materials research tools based on X-ray technology. Bruker Daltonics is a leading developer and provider of innovative life science tools based on mass spectrometry. For more information, please visit www.bruker-biosciences.com.
CAUTIONARY STATEMENT
Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. Any forward-looking statements contained herein are based on current expectations, but are subject to a number of risks and uncertainties. The factors that could cause actual future results to differ materially from current expectations include, but are not limited to, risks and uncertainties relating to the Company's reorganization strategies, integration risks, failure of conditions, technological approaches, product development, market acceptance, cost and pricing of the Company's products, changes in governmental regulations, capital spending and government funding policies, FDA and other regulatory approvals to the extent applicable, competition, the intellectual property of others, patent protection and litigation. These and other factors are identified and described in more detail in our filings with the SEC, including, without limitation, our annual report on Form 10-K for the year ended December 31, 2003, our most recent quarterly reports on Form 10-Q and our current reports on Form 8-K. We disclaim any intent or obligation to update these forward-looking statements.
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